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Jonathan Knisely, M.D., FRCPC
Associate Professor
Yale University School of Medicine
Department of Therapeutic Radiology
P.O. Box 208040
New Haven, CT 06520-8040
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Contact Info
Cheryl Soltysik 203-785-2960
Allison Lehman 203-688-1861
Fax: 203-785-6527 or 203-785-4622
Biosketch
Jonathan Knisely is an Associate Professor in Yale University School
of Medicine's Department of Therapeutic Radiology. He sees patients with
benign and malignant tumors that arise in or spread to the brain to discuss
the role that radiotherapy can play in the management of these conditions.
His area of particular expertise is in the use of radiation to treat brain
tumors.
Treatment for individual patients may involve stereotactic radiosurgery
using the Gamma Knife, intensity modulated radiation therapy (IMRT), three-dimensional
conformal radiation therapy, brachytherapy, and other methods designed
to maximize the chance of tumor control and preserve quality of life.
Dr. Knisely takes particular care in the design and supervision of the
radiation treatment of patients with brain tumors; image fusion between
MRI and CT has been used at Yale for planning radiotherapy treatments
to the brain since 1996. Dr. Knisely is active in the clinical research
efforts of the Yale Brain Tumor Center and is Yale’s Principal Investigator
for the Radiation Therapy Oncology Group (RTOG). His other research interests
include hypoxia in brain tumors and the use of radiation sensitizers to
maximize radiation’s effect on tumors.
Education
1982 |
BA - East Asian Language
and Literature (Chinese) |
Yale University, New Haven,
CT |
1982 |
BS - Molecular Biophysics
and Biochemistry |
Yale University, New Haven,
CT |
1986 |
Doctor of Medicine |
University of Pennsylvania,
Philadelphia, PA |
1989 |
Internal Medicine Residency |
Michael Reese Hospital,
Chicago, IL |
| 1992 |
Radiation Oncology Residency |
University of Toronto,
Princess Margaret Hospital Toronto, ON |
Selected Peer-reviewed Publications
Knisely J “Conformal radiotherapy for high-grade gliomas: how much
is too much?” Journal of Clinical Oncology 2002;20:3357-8; discussion
3359.
Knisely JP, Bond JE, Yue NJ, Studholme C, deLotbiniere AC “Image
registration and calculation of a biologically effective dose for multisession
radiosurgical treatments. Technical note.” Journal of Neurosurgery,
93(Suppl 3):208-18, 2000.
Heath EI, Burtness BA, Heitmiller RF, Salem RR, Kleinberg LR, Knisely
JPS, Yang SC, Talamini MA, Kaufman HS, Canto MI, Topazian MD, Wu T-T,
Olukayode K, Forastiere AA. “Phase II Evaluation of Pre-operative
Chemoradiation and Post-operative Adjuvant Chemotherapy for Squamous Cell
Carcinoma and Adenocarcinoma of the Esophagus.” Journal of Clinical
Oncology, 18:868-76, 2000.
deLotbiniere A, Lee S, Nijensohn D, Knisely J, Roberts K “Gamma
knife stereotactic radiosurgical treatment for refractory trigeminal neuralgia.”
Stereotactic and Functional Neurosurgery, 73:71, 1999.
Zeng M, Knisely JPS. “Post-Radiotherapy Myelitis Observed in an
AIDS Patient with a Meningioma. Case Report and Review of the Literature.”
Journal of Neuro-Oncology, 45:167-74, 1999.
Collingridge D, Piepmeier J, Rockwell S, and Knisely JPS. “Polarographic
Measurements of Oxygen Tension in Human Glioma and Surrounding Peritumoural
Brain Tissue.” Radiotherapy and Oncology, 53:127-131, 1999.
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